Boron doped diamond microelectrodes arrays for electrochemical detection in HPLC

• Boron-doped diamond microelectrodes arrays have been used as sensors for HPLC.
• These amperometric sensors have a good signal/noise ratio.
• Spacing, disposition and number of the microelectrodes have been studied, as well as influence of flow velocity.

Boron doped diamond microelectrodes arrays (MEA) have been prepared in order to be used as new amperometric sensors in electrochemical cells for HPLC detectors. The following parameters were studied: number and diameter (15–40 µm) of the electrodes, distance between them (50–240 µm), and effect of the flow rate (0.1–3 mL/min). It was thus possible to find the optimum value of the parameters which give a good signal/noise ratio in the chronoamperometric responses, with a size of the electrochemical sensors as small as possible.

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