کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1242528 969637 2011 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Sensitive voltammetric determination of baicalein at DNA Langmuir–Blodgett film modified glassy carbon electrode
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Sensitive voltammetric determination of baicalein at DNA Langmuir–Blodgett film modified glassy carbon electrode
چکیده انگلیسی

The present paper describes to modify a double stranded DNA–octadecylamine (ODA) Langmuir–Blodgett film on a glassy carbon electrode (GCE) surface to develop a voltammetric sensor for the detection of trace amounts of baicalein. The electrode was characterized by atomic force microscopy (AFM) and cyclic voltammetry (CV). Electrochemical behaviour of baicalein at the modified electrode had been investigated in pH 2.87 Britton–Robinson buffer solutions by CV and square wave voltammetry (SWV). Compared with bare GCE, the electrode presented an electrocatalytic redox for baicalein. Under the optimum conditions, the modified electrode showed a linear voltammetric response for the baicalein within a concentration range of 1.0 × 10−8–2.0 × 10−6 mol L−1, and a value of 6.0 × 10−9 mol L−1 was calculated for the detection limit. And the modified electrode exhibited an excellent immunity from epinephrine, dopamine, glucose and ascorbic acid interference. The method was also applied successfully to detect baicalein in the medicinal tablets and spiked human blood serum samples with satisfactory results.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Talanta - Volume 84, Issue 1, 15 March 2011, Pages 160–168
نویسندگان
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