کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1242943 | 1495832 | 2013 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Determination of microcystin-LR in water by a label-free aptamer based electrochemical impedance biosensor Determination of microcystin-LR in water by a label-free aptamer based electrochemical impedance biosensor](/preview/png/1242943.png)
In this study, an electrochemical impedance biosensor for cyanobacterial toxin microcystin-LR (MC-LR) detection has been developed. MC-LR aptamers were immobilized on the gold electrode through Au–S interaction, in the presence of target (MC-LR); the binding of MC-LR and aptamers probe led to a complex formation change on the electrode surface and resulted in the impedance decreasing. The decrease rate had a linear relationship with logarithm of the MC-LR concentration in the range of 1.0×10−7–5.0×10−11 mol/L, with a detection limit of 1.8×10−11 mol/L. The sensor has good selectivity and stability, it has been applied to detect MC-LR in three kinds of real water samples with satisfying results.
► Sensitive and selective biosensor for MC-LR detection has been developed.
► The sensor combined the advantages of aptamer and impedance detection.
► The sensor has been applied to detect MC-LR in real water samples with satisfying results.
Journal: Talanta - Volume 103, 15 January 2013, Pages 371–374