Solenoid micropump-based flow system for generalized calibration strategy

• The designed flow system is dedicated to the generalized calibration strategy.
• The flow manifold was used to determine calcium in real samples via FAAS.
• The advantages and drawbacks of the flow system have been presented and discussed.
• The performance of the generalized calibration strategy has been demonstrated.

Generalized calibration strategy (GCS) is one of the innovative approaches aimed at verification and improvement of accuracy of analytical determinations. It combines in a single procedure the interpolative and the extrapolative calibration approaches along with stepwise dilution of a sample with the use of a dedicated flow system. In the paper a simple solenoid micropump-based flow system designed for implementation of GCS has been described. The manifold consists of several modules fully operated by a computer and connected with each other in a properly designed network. Its performance and usefulness were tested on determination of calcium by FAAS in synthetic and natural samples containing strong interferents. It was shown how GCS can serve for detection, examination and elimination of the interference effects. It was demonstrated that the designed manifold enabled to perform GCS procedure with very good precision, in short time and with very low standard, sample and reagent consumption.

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