کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1245459 969723 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Rapid analysis of clenbuterol, salbutamol, procaterol, and fenoterol in pharmaceuticals and human urine by capillary electrophoresis
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Rapid analysis of clenbuterol, salbutamol, procaterol, and fenoterol in pharmaceuticals and human urine by capillary electrophoresis
چکیده انگلیسی

Capillary electrophoresis (CE) with UV detection for the simultaneous and short-time analysis of clenbuterol, salbutamol, procaterol, fenoterol is described and validated. Optimized conditions were found to be a 10 mmol l−1 borate buffer (pH 10.0), an separation voltage of 19 kV, and a separation temperature of 32 °C. Detection was set at 205 nm. Under the optimized conditions, analyses of the four analytes in pharmaceutical and human urine samples were carried out in approximately 1 min. The interference of the sample matrix was not observed. The LOD (limits of detection) defined at S/N of 3:1 was found between 0.5 and 2.0 mg l−1 for the analytes. The linearity of the detector response was within the range from 2.0 to 30 mg l−1 with correlation coefficient >0.996.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Talanta - Volume 76, Issue 5, 15 September 2008, Pages 1194–1198
نویسندگان
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