Liquid-phase microextraction

The development of faster, simpler, inexpensive and more environmentally-friendly sample-preparation techniques is an important issue in chemical analysis.Recent research trends involve miniaturization of the traditional liquid-liquid-extraction principle by greatly reducing the acceptor-to-donor ratio.The current trend is towards simplification and miniaturization of sample preparation and decreasing the quantities of organic solvents used.We discuss liquid-phase microextraction with the focus on extraction principles, historical development and performance.