کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1251858 1496301 2013 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Electrochemical impedance spectroscopy as a method for electrical characterization of the bilayers formed from lipid-amino acid systems
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Electrochemical impedance spectroscopy as a method for electrical characterization of the bilayers formed from lipid-amino acid systems
چکیده انگلیسی


• The effect of amino acids on physicochemical parameters of the phosphatidylcholine membranes.
• Determination of surface area of phosphatidylcholine–amino acid domains.
• Application of electrochemical impedance spectroscopy to the research of lipid bilayers.

Bilayer lipid membranes composed of phosphatidylcholine and isoleucine or phosphatidylcholine and tyrosine were investigated using electrochemical impedance spectroscopy. Interaction between membrane components causes significant deviations from the additivity rule which can be explained by formation of the domain structures. The surface area of domains was calculated based on derived equations. We suggest that the stoichiometry of phosphatidylcholine–isoleucine domain is equal 3:1. In the case of tyrosine-modified phosphatidylcholine membranes, domain with stoichiometry 7:1 should be taken into consideration.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemistry and Physics of Lipids - Volumes 175–176, October–November 2013, Pages 116–122
نویسندگان
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