Metal complexes for the detection of disease-related protein biomarkers

• Metal complexes used in construction of DNA-based sensing platforms are described.
• Recent chemosensors for disease-related protein biomarkers are summarized.
• Applications of metal complex for the detection of protein biomarkers are discussed.

The detection of pathological biomarkers can allow for the early diagnosis and treatment of human disease, lowering morbidity and improving quality of life. Transition metal complexes have recently found use as luminescent probes for the detection of protein biomarkers. In this review, we highlight recent examples of metal complexes that have been used in DNA-based sensing platforms or as chemosensors for protein biomarkers.