Synthesis, structural and in vitro functional characterization of arene ruthenium complexes with 1,3,5-tris(di-2-pyridylaminomethyl)benzene ligand

Mono, di and trinuclear half sandwich ruthenium complexes with 1,3,5-tris(di-2-pyridylaminomethyl) benzene have been synthesized, characterized and their activity over four pathogenic bacteria and four cancer lines have been assessed. Antibacterial activity against four bacteria viz Staphylococcus aureus MTCC96; Escherichia coli MTCC739; Klebsiella pneumonia MTCC2653 and Pseudomonas aeruginosa MTCC2453. Antiproliferative activity against four cancer cell lines viz B16F10 (Mouse melanoma carcinoma), THP-1 (Human acute monocytic leukemia), PC3 (Human prostate carcinoma) and SK-OV-3 (Human ovarian carcinoma).96