کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1327763 | 977502 | 2009 | 5 صفحه PDF | دانلود رایگان |
The catalytic system based on Pd–phosphite for the dehalogenation reactions of aryl chlorides and bromides is described. The Pd–phosphite catalyst effectively promoted the dehalogenation of aryl halides to give dehalogenated products in moderate to excellent yields. The aryl chlorides required strong bases such as NaOtBu for this transformation, whereas the aryl bromides were dehalogenated in the presence of weak bases such as Cs2CO3. This catalytic system exhibited tolerance to functional groups such as methoxy, amine, hydroxyl, ether, amide, benzyl and ketone groups. It also demonstrated chemoselectivity in that bromochlorobenzene was converted only to chlorobenzene.
The Pd–phosphite catalyst effectively promoted the dehalogenation of aryl halides to give dehalogenated products in moderate to excellent yields. The aryl chlorides required strong bases such as NaOtBu for this transformation, whereas the aryl bromides were dehalogenated in the presence of weak bases such as Cs2CO3.Figure optionsDownload as PowerPoint slide
Journal: Journal of Organometallic Chemistry - Volume 694, Issue 3, 1 February 2009, Pages 473–477