QSAR studies of N1-(5-chloro-2-pyridyl)-2-{[4-(alkyl methyl)benzoyl]amino}-5-chlorobenzamide analogs

The paper deals with the quantitative structure-activity relationship study on an anthranilamide-based factor Xa inhibitory activity as a function of physico-chemical parameters and predicts the best factor Xa inhibitory compound. The predictive power of the proposed models is discussed on the basis of regression analysis and cross-validation parameters.