Theoretical analysis of the retention behavior of alcohols in gas chromatography

Retention times (t) of 10 standard samples were determined for alcohols and ethyl acetate. An SP-2305 gas chromatograph (China) coupled with a hydrogen flame temperature detector with a (polarity stationary phase of Superox 20M:diglycerol:101 white support (0.177-0.25 mm i.d.) = 20:2:100) stainless steel column (3 m × 4 mm i.d.) was used. Nitrogen gas was used as a carrier gas at a flow rate of 50.0 mL/min. A 1 μL volume of sample (0.3 μg/μL every standard sample in mixture of ethanol and water 60:40 (v/v)) was injected in vaporizer. Temperatures of the vaporizer, the column and the detector were set at 125, 79, and 110 °C, respectively. The t values of alcohols and ethyl acetate on stationary phases were regressed versus each one of the descriptors, quantitative structure-retention relationship (QSRR) models for the chromatographic (GC) retention times of alcohols on Superox 20M-diglycerol polarity stationary phase have been developed.