Syntheses of novel heterocycles as anticancer agents

Several pteridine analogues 4–13, 23–26 have been synthesized and tested in vitro against three cancer cell lines, MCF7 (breast), NCI-H460 (lung) and SF-268 (CNS). All tested pteridines can serve as novel templates for the anticancer chemotherapy and can serve as new leads in cancer chemotherapy.

Several pteridine analogues 4–13, 23–26 have been synthesized and tested in vitro against three cancer cell lines, MCF7 (breast), NCI-H460 (lung) and SF-268 (CNS).Figure optionsDownload as PowerPoint slide