کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1379683 | 982035 | 2008 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Alginate–calcium carbonate porous microparticle hybrid hydrogels with versatile drug loading capabilities and variable mechanical strengths
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Alginate–calcium carbonate porous microparticle hybrid hydrogels with versatile drug loading capabilities and variable mechanical strengths Alginate–calcium carbonate porous microparticle hybrid hydrogels with versatile drug loading capabilities and variable mechanical strengths](/preview/png/1379683.png)
چکیده انگلیسی
Novel alginate/porous CaCO3 microparticle hybrid hydrogels are facilely fabricated by in-situ release of Ca2+ from CaCO3 microparticles induced by hydrolysis of d-glucono-δ-lactone to reduce pH. The mechanical strength of hybrid hydrogels is easily tunable by the alginate/CaCO3 weight ratio. IBU was adsorbed into the porous CaCO3 microparticles. The embedded porous CaCO3 microparticles endow alginate hydrogels versatile drug loading capability and sustained release, especially for less water-soluble substances. This methodology provides a novel way to create new hybrid hydrogels for biomedical applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 71, Issue 3, 8 February 2008, Pages 476–480
Journal: Carbohydrate Polymers - Volume 71, Issue 3, 8 February 2008, Pages 476–480
نویسندگان
Chaoyang Wang, Hongxia Liu, Quanxing Gao, Xinxing Liu, Zhen Tong,