The structure of the polysaccharide isolated from Acinetobacter baumannii strain LAC-4

• Acinetobacter baumannii is an important human pathogen.
• LPS is one of the bacterial virulence factors.
• The structure of the polysaccharide part of the LPS from a hypervirulent for mice strain LAC-4 was studied.
• 8-epi-Legionaminic acid was found in the polysaccharide.

The structure of the surface polysaccharide from a hypervirulent for mice Acinetobacter baumannii strain LAC-4 was studied. The polysaccharide was built of trisaccharide repeating units containing α-l-fucosamine, α-d-glucosamine, and α-8-epi-legionaminic acid. The structure interpretation was based mostly on NMR data. Polysaccharide was obtained using a procedure of LPS O-chain preparation, although whether it is an LPS O-chain or capsular polysaccharide remained unclear.

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