Solvatochromism, spectral properties and antimicrobial activities of new azo–azomethine dyes with N2S2O2 donor set of atoms

• New bisiminated water insoluble azo–azomethine dyes have synthesized.
• Solvatochromic properties of the dyes in various organic solvents have been investigated.
• Aantimicrobial activities of the prepared dyes have been reported.

Six new azo–azomethine dyes, H2Ln (n = 1–6), with N2S2O2 donor set of atoms have been prepared via condensation reaction of 1,10-diaza-4,7-dithiadecane, I, with substituted azo-coupled salicylaldehyde. The dyes were characterized by IR, UV–Vis and 1H NMR spectroscopic methods as well as elemental analysis. The solvatochromic behavior of the dyes was also probed by studying their UV–Vis spectra in four pure organic solvents of different polarities and a meaningful correlation was observed. Furthermore, all prepared dyes were assayed for their antibacterial and antifungal activities by disc diffusion method. The results indicated that all prepared dyes show good inhibition against Staphylococcus epidermidis and Bacillus cereus and did not show any antibacterial activity against Escherichia coli as compared to standard drugs.

New azo–azomethine dyes have been prepared via condensation reaction of 1,10-diaza-4,7-dithiadecane with substituted azo-coupled salicylaldehyde. The UV–Vis spectra of the dyes in pure organic solvents of different polarities and their antimicrobial activities have been investigated.Figure optionsDownload as PowerPoint slide