The fifth solvatomorph of gallic acid with a supramolecular channel structure: Structural complexity and phase transitions

A new solvatomorph of gallic acid was generated using chiral additive technique and characterized by single crystal and powder X-ray diffraction, C-13 NMR, IR spectroscopic techniques and thermal analysis. The supramolecular channels formed by hexameric motifs of gallic acid and solvent molecules contain highly disordered solvent molecules with fractional occupancies.

► The crystal structure of fifth solvatomorph of gallic acid.
► Crystal form generated by chiral additive.
► Supramolecular channel structure with highly disordered solvents.
► Phase transition studies show the uniqueness of anhydrous form.
► “Hydration synthons” formed by water molecules analyzed.