Comparing the interaction of vanadyl-hypocrellin A complex and hypocrellin A with CT DNA

► VO2+-HA complex and HA could both bind to CT DNA.► The fluorescence quenching mechanisms by VO2+-HA or HA were static quenching.► The binding force between HA and CT DNA was hydrophobic force.► The binding force between VO2+-HA and CT DNA was electrostatic force.