کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1408301 1501736 2015 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis and crystal structure of copper (II) uracil ternary polymeric complex with 1,10-phenanthroline along with the Hirshfeld surface analysis of the metal binding sites for the uracil ligand
ترجمه فارسی عنوان
سنتز و ساختار کریستالی مجتمع پلیمری سه جانبه اوراسیل مسی با 1،10-فنانترولین همراه با تحلیل سطح هیرشفلد سایت های اتصال فلز برای لیگاند اوراسیل
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
چکیده انگلیسی


• Ternary complex of copper-uracil-phenanthroline as a biomimic model.
• The complexes crystallized as solvatomorphs.
• Unique binding of uracil with N1 and N3 nitrogen atom of the six membered ring.
• First 1-D polymer with uracil as bridging ligand.
• Subtle differences of solvatomorphs quantified with Hirshfeld surface analysis.

The study of models for “metal-enzyme-substrate” interaction has been a proactive area of research owing to its biological and pharmacological importance. In this regard the ternary copper uracil complex with 1,10-phenanthroline represents metal-enzyme-substrate system for DNA binding enzymes. The synthesis of the complex, followed by slow evaporation of the reaction mixture forms two concomitant solvatomorph crystals viz., {[Cu(phen)(μ-ura)(H2O)]n·H2O (1a)} and {[Cu(phen)(μ-ura)(H2O)]n·CH3OH (1b)}. Both complexes are structurally characterized, while elemental analysis, IR and EPR spectra were recorded for 1b (major product). In both complexes, uracil coordinates uniquely via N1 and N3 nitrogen atom acting as a bidentate bridging ligand forming a 1-D polymer. The two solvatomorphs were quantitatively analyzed for the differences with the aid of Hirshfeld surface analysis.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Structure - Volume 1081, 5 February 2015, Pages 14–21
نویسندگان
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