Application of carbon nanotubes-ionic liquid hybrid in a sensitive atorvastatin ion-selective electrode

Graphite paste was modified with atorvastatin-CTAB (ATR-CTAB), ionic liquid (BMIMPF6) and multiwalled carbon nanotubes (MWCNTs). It was used in potentiometric analysis of nanomolar concentrations of atorvastatin in different samples. The method had one of the lowest limits of detection (LOD) among the methods reported for the drug analysis. Excellent reproducibility and accuracy was obtained in complex matrices such as blood serum and urine.46