One-step synthesis of aldehyde-functionalized magnetic nanoparticles as adsorbent for fast and effective adsorption of proteins

Novel directly aldehyde-functionalized magnetic nanoparticles were synthesized using a facile one-pot solvothermal method with glutaraldehyde as modification ligand. The as-synthesized nanoparticles exhibited a narrow size distribution, highly crystalline, and superparamagnetic properties. The obtained products possessed high saturation magnetization of 32.84 emu g−1, which made them to be easily separated from solution by means of an external magnetic field. Moreover, the resultant functionalized magnetic nanomaterials were successfully applied for protein adsorption with high amount through reversible imine bond.