کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1760570 | 1019609 | 2012 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Correlation and Agreement Between Contrast-Enhanced Ultrasonography and Perfusion Computed Tomography for Assessment of Liver Metastases from Endocrine Tumors: Normalization Enhances Correlation
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کلمات کلیدی
Angiogenesis - آنژیوژنزContrast-enhanced ultrasonography - اولتراسونوگرافی با افزایش کنتراستPerfusion imaging - تصویربرداری تصویربرداریFunctional imaging - تصویربرداری عملکردیEndocrine tumor - تومور غدد درون ریزMetastasis - متاستاز Microbubbles - میکرو حبابBiomarkers - نشانگر زیستی یا بیومارکرLiver - کبد
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
آکوستیک و فرا صوت
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
We studied correlation and agreement between perfusion parameters derived from contrast-enhanced ultrasonography (CEUS) and computed tomography (CT). Both techniques were performed in 16 patients with proven liver metastases from endocrine tumor. Replenishment study after ultrasound-induced destruction of microbubbles was used for CEUS quantification. CEUS-derived relative values of blood flow, blood volume and mean transit time were compared with perfusion CT-derived parameters measured in the same tumors. Significant correlation was observed between CEUS normalized values and CT absolute tumor values for blood flow (r = 0.58; p = 0.018), blood volume (r = 0.61; p = 0.012) and mean transit time (r = 0.52; p = 0.037). Correlation was not significant for non-normalized values. Agreement between CEUS normalized values and perfusion CT relative values was significant (p < 0.04). Estimated bias between CEUS and CT for relative perfusion values was â1.38 (â5.02; 2.27) for blood flow, +0.26 (â0.79; 1.31) for blood volume and +0.21 (â0.46; 0.87) for mean transit time. We conclude that normalization markedly increased correlation between CEUS- and CT-derived perfusion values and allowed agreement assessment.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 38, Issue 6, June 2012, Pages 953-961
Journal: Ultrasound in Medicine & Biology - Volume 38, Issue 6, June 2012, Pages 953-961
نویسندگان
Thibaud Lefort, Frank Pilleul, Sébastien Mulé, S. Lori Bridal, Frédérique Frouin, Catherine Lombard-Bohas, Thomas Walter, Olivier Lucidarme, Aymeric Guibal,