کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1762880 1019723 2006 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Assessment by transient elastography of the viscoelastic properties of blood during clotting
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم آکوستیک و فرا صوت
پیش نمایش صفحه اول مقاله
Assessment by transient elastography of the viscoelastic properties of blood during clotting
چکیده انگلیسی
Blood clotting is a natural process that can be both beneficial and life-threatening for the human body. It allows the maintenance of hemostasis after vascular injury, but it can also cause deep vein thrombosis and heart stroke. This study aimed better to understand the clotting process from a biomechanical point of view by using an acoustic method. The long-term objective is the staging of the age of clots in deep veins for therapy planning. The transient elastography method using a shear elasticity probe served to evaluate the shear wave velocity (VS) and shear wave attenuation (αS) of porcine whole blood during in vitro clot formation. By solving an inverse problem, it was then possible to provide images of the elasticity (μB) and of the viscosity (ηB) from clotting blood. The time-varying elasticity and viscosity were very similar to what has been observed for the sol-gel transition of polymers. The mechanical properties of blood clot, which were modified by varying the hematocrit and by adding heparin or fibrinogen, were clearly assessed by the transient elastography technique. It is concluded that the shear elasticity probe is an appropriate tool to quantify and follow the sol-gel transition of blood during clotting. (E-mail: guy.cloutier@umontreal.ca)
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 32, Issue 10, October 2006, Pages 1529-1537
نویسندگان
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