کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1880095 1042881 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Is there a clinical benefit with a smooth compensator design compared with a plunged compensator design for passive scattered protons?
ترجمه فارسی عنوان
آیا یک مزیت بالینی با یک طراحی جبران کننده صاف در مقایسه با یک طراحی جبران کننده غرق شده برای پروتون های پراکنده منفرد وجود دارد؟
کلمات کلیدی
پروتون، جبران کننده صاف، جبران کننده عمق تخلیه شده، غرق شدن، صیقلی خرد شده، پروتون پراکنده منفعل، جبران کننده،
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم تشعشع
چکیده انگلیسی
In proton therapy, passive scattered proton plans use compensators to conform the dose to the distal surface of the planning volume. These devices are custom made from acrylic or wax for each treatment field using either a plunge-drilled or smooth-milled compensator design. The purpose of this study was to investigate if there is a clinical benefit of generating passive scattered proton radiation treatment plans with the smooth compensator design. We generated 4 plans with different techniques using the smooth compensators. We chose 5 sites and 5 patients for each site for the range of dosimetric effects to show adequate sample. The plans were compared and evaluated using multicriteria (MCA) plan quality metrics for plan assessment and comparison using the Quality Reports [EMR] technology by Canis Lupus LLC. The average absolute difference for dosimetric metrics from the plunged-depth plan ranged from −4.7 to +3.0 and the average absolute performance results ranged from −6.6% to +3%. The manually edited smooth compensator plan yielded the best dosimetric metric, +3.0, and performance, + 3.0% compared to the plunged-depth plan. It was also superior to the other smooth compensator plans. Our results indicate that there are multiple approaches to achieve plans with smooth compensators similar to the plunged-depth plans. The smooth compensators with manual compensator edits yielded equal or better target coverage and normal tissue (NT) doses compared with the other smooth compensator techniques. Further studies are under investigation to evaluate the robustness of the smooth compensator design.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medical Dosimetry - Volume 40, Issue 1, Spring 2015, Pages 37-43
نویسندگان
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