کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1880843 | 1399972 | 2016 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Evaluation of the setup margins for cone beam computed tomography-guided cranial radiosurgery: A phantom study
ترجمه فارسی عنوان
ارزیابی حاشیه های نصب شده برای پرتو مخروطی رادیوس جراحی مغناطیسی تحت جراحی توموگرافی: یک مطالعه فانتوم
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
تشعشع
چکیده انگلیسی
The aim of this study is to evaluate the setup margins from the clinical target volume (CTV) to planning target volume (PTV) for cranial stereotactic radiosurgery (SRS) treatments guided by cone beam computed tomography (CBCT). We designed an end-to-end (E2E) test using a skull phantom with an embedded 6mm tungsten ball (target). A noncoplanar plan was computed (E2E plan) to irradiate the target. The CBCT-guided positioning of the skull phantom on the linac was performed. Megavoltage portal images were acquired after 15 independent deliveries of the E2E plan. The displacement 2-dimensional (2D) vector between the centers of the square field and the ball target on each portal image was used to quantify the isocenter accuracy. Geometrical margins on each patient׳s direction (left-right or LR, anterior-posterior or AP, superior-inferior or SI) were calculated. Dosimetric validation of the margins was performed in 5 real SRS cases: 3-dimesional (3D) isocenter deviations were mimicked, and changes in CTV dose coverage and organs-at-risk (OARs) dosage were analyzed. The CTV-PTV margins of 1.1 mm in LR direction, and 0.7 mm in AP and SI directions were derived from the E2E tests. The dosimetric analysis revealed that a 1-mm uniform margin was sufficient to ensure the CTV dose coverage, without compromising the OAR dose tolerances. The effect of isocenter uncertainty has been estimated to be 1 mm in our CBCT-guided SRS approach.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medical Dosimetry - Volume 41, Issue 3, Autumn 2016, Pages 199-204
Journal: Medical Dosimetry - Volume 41, Issue 3, Autumn 2016, Pages 199-204
نویسندگان
Juan Francisco M.Sc., Wouter Ph.D., David M.D., Sandra R.T.T., Miquel R.T.T., Joan M.D.,