The effect of selected zwitterionic surfactant on the structure of hydrated DMPC

Differential scanning calorimetry, Fourier transformed infrared (FTIR) spectroscopy and small angle scattering of synchrotron radiation have been used to analyse the influence of zwitterionic surfactant (3-(N-hexylmorpholine)-1-propansulfonate) on the conformational dynamics of CH2 and CH3 groups of 1,2-dimyrilstoyl-sn-glycero-3-phosphocholine (DMPC) and the phase behaviour of phospholipid bilayers. The surfactant causes changes in the DMPC phase transition temperature and promotes a gradual disappearance of the lamellar phase of DMPC and a probable formation of the bicellar phase.