کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1885867 | 1533499 | 2016 | 7 صفحه PDF | دانلود رایگان |
• γ-ray sterilization of single-use plastic bags for biotechnology and biopharmaceutical applications.
• Use of ATR-FTIR spectroscopy to monitor the modifications of γ-irradiated polymers over time.
• Interpretation and highlighting of slight spectral variations after multiple absorbed doses using chemometric methods.
The multilayer films made of polyethylene/polyethylene-co-vinyl alcohol/polyethylene are γ-irradiated for biopharmaceutical and biotechnological applications. The radiations generate changes in the polymer films. In this study, we focused on the modifications produced on the surface of materials by Fourier transformed infrared (FTIR) spectroscopy combined with chemometric treatments. Principal component analysis (PCA) allows the ordering of the surface modifications according to absorbed doses and the natural ageing. Results show the rising of the acid band and the variation of unsaturated compounds.
Figure optionsDownload as PowerPoint slide
Journal: Radiation Physics and Chemistry - Volume 125, August 2016, Pages 115–121