کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
191010 459713 2011 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Electrochemical determination of cysteine based on conducting polymers/gold nanoparticles hybrid nanocomposites
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Electrochemical determination of cysteine based on conducting polymers/gold nanoparticles hybrid nanocomposites
چکیده انگلیسی

In this study, a hybrid nanocomposite consisting of a conducting polymer and gold nanoparticles (AuNPs) is fabricated onto a screen-printed carbon electrode (SPCE). A thin layer of poly(3,4-ethylenedioxythiophene) (PEDOT) is coated electrochemically on a bare SPCE; then, the nano-sized AuNPs are embedded by electrochemical deposition. The resultant SPCE/PEDOT/AuNPs-modified electrode is characterized by electrochemical methods, field emission scanning electron microscopy (FE-SEM) and X-ray photoelectron spectroscopy (XPS). The SPCE/PEDOT/AuNPs-modified electrode possesses great catalytic activity for the oxidation of cysteine in various pH buffer solutions (pH 2.0–8.0). The selectivity of the method is demonstrated by the separation of the oxidation peaks at up to 240 mV for cysteine and glutathione in pH 6.0 buffer solutions. The effects of the oxidizable interferences are also investigated. Flow-injection amperometry is performed for 0.5–200 μM of cysteine in pH 4.0 buffer solutions, and a linear calibration plot with a slope of 0.115 μA/μM is obtained. The detection limit (S/N = 3) is 0.05 μM. Additionally, the proposed methods obtain satisfactory results in the detection of cysteine-containing medicine samples.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Electrochimica Acta - Volume 56, Issue 20, 1 August 2011, Pages 6887–6895
نویسندگان
, , , ,