کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
192657 459748 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Electrocatalytic tandem Knoevenagel–Michael reaction of 3-methyl-2-pyrazolin-5-ones, aryl aldehydes and cyano-functionalized C–H acids: Facile and convenient multicomponent way to substituted 3-(5-hydroxy-3-methylpyrazol-4-yl)-3-arylpropionitriles
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Electrocatalytic tandem Knoevenagel–Michael reaction of 3-methyl-2-pyrazolin-5-ones, aryl aldehydes and cyano-functionalized C–H acids: Facile and convenient multicomponent way to substituted 3-(5-hydroxy-3-methylpyrazol-4-yl)-3-arylpropionitriles
چکیده انگلیسی

Electrochemically induced catalytic tandem Knoevenagel–Michael reaction of 3-methyl-2-pyrazolin-5-ones, aryl aldehydes and malononitrile or alkyl cyanoacetates in alcohols in an undivided cell in the presence of sodium bromide as an electrolyte results in the formation of substituted 3-(5-hydroxy-3-methylpyrazol-4-yl)-3-arylpropionitriles in 75–97% yields. The developed efficient electrocatalytic approach to the corresponding 3-(5-hydroxy-3-methylpyrazol-4-yl)-3-arylpropionitriles is beneficial from the viewpoint of diversity-oriented large-scale processes and represents novel, facile and environmentally benign synthetic concept for multicomponent reactions strategy.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Electrochimica Acta - Volume 53, Issue 15, 1 June 2008, Pages 5033–5038
نویسندگان
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