کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1926656 1536474 2008 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mutational analysis of ABC proteins
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Mutational analysis of ABC proteins
چکیده انگلیسی
The 49 human members of the ATP-binding cassette (ABC) family of proteins are involved in a wide range of activities such as active transport of compounds across membranes, extraction of compounds out of membranes, functioning as ion channels, or regulators of channel activity. Mutations and/or overexpression of many of the proteins can have adverse effects on health. A goal in the study of ABC proteins is to understand their mechanisms of action. This review will focus on the mutational approaches that have been used to study the structure and mechanisms of some ABC proteins.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Biochemistry and Biophysics - Volume 476, Issue 1, 1 August 2008, Pages 51-64
نویسندگان
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