کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
192780 459751 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A novel DNA biosensor based on ssDNA/Cyt c/l-Cys/GNPs/Chits/GCE
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
A novel DNA biosensor based on ssDNA/Cyt c/l-Cys/GNPs/Chits/GCE
چکیده انگلیسی

A novel DNA biosensor was fabricated by modified multilayer of ssDNA, cytochrome c, l-cysteine, metal gold nanoparticles and Chitosan (denoted as ssDNA/Cyt c/l-Cys/GNPs/Chits/GCE). The behavior of the DNA biosensor was then investigated by voltammetry, impedance spectrum and atomic force microscope (AFM), and the morphologic differences among each layer of the DNA biosensor were also observed. Results revealed that two well-defined redox peaks exhibited at 0.120 V and 0.362 V, and the amount of adsorbed DNA was 1.672 × 10−10 mol cm−2. We concluded that the modified electrode could be used to detect DNA with the indicator daunomycin.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Electrochimica Acta - Volume 54, Issue 8, 1 March 2009, Pages 2284–2289
نویسندگان
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