Neodymium (III) hexacyanoferrate (II) nanoparticles induced by enzymatic reaction and their use in biosensing of glucose

The formation of neodymium (III) hexacyanoferrate (II) (NdHCF) nanoparticles (NPs) on the surface of carbon-paste electrode induced by enzymatic reaction was described and characterized. The conditions for biosensing of glucose were optimized through various experiments. Results showed that the optimized condition of the glucose oxidase (GOx)-induced NdHCF NPs for the biosensing of glucose were 2.0 mM Nd3+, 40.0 mM Fe(CN)63− and 20 μg/mL GOx. The biocatalyzed generation of NdHCF NPs in the presence of O2/glucose and GOx enabled the development of an electrochemical biosensor for glucose. Furthermore, this system avoids the interferences from other species for the biosensing of glucose.