کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1984596 1539943 2010 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Fibrocytes: Bringing new insights into mechanisms of inflammation and fibrosis
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Fibrocytes: Bringing new insights into mechanisms of inflammation and fibrosis
چکیده انگلیسی

Regeneration and fibrosis are integral parts of the recovery process following tissue injury, and impaired regulation of these mechanisms is a hallmark of many chronic diseases. A population of bone marrow-derived mesenchymal progenitor cells known as fibrocytes, play an important role in tissue remodeling and fibrosis in both physiologic and pathologic settings. In this review we summarize the key concepts regarding the pathophysiology of wound healing and fibrosis, and present data to support the contention that circulating fibrocytes are important in both normal repair process and aberrant healing and fibrotic damage associated with a diverse set of disease states.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The International Journal of Biochemistry & Cell Biology - Volume 42, Issue 4, April 2010, Pages 535–542
نویسندگان
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