کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1984596 | 1539943 | 2010 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Fibrocytes: Bringing new insights into mechanisms of inflammation and fibrosis
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Fibrocytes: Bringing new insights into mechanisms of inflammation and fibrosis Fibrocytes: Bringing new insights into mechanisms of inflammation and fibrosis](/preview/png/1984596.png)
چکیده انگلیسی
Regeneration and fibrosis are integral parts of the recovery process following tissue injury, and impaired regulation of these mechanisms is a hallmark of many chronic diseases. A population of bone marrow-derived mesenchymal progenitor cells known as fibrocytes, play an important role in tissue remodeling and fibrosis in both physiologic and pathologic settings. In this review we summarize the key concepts regarding the pathophysiology of wound healing and fibrosis, and present data to support the contention that circulating fibrocytes are important in both normal repair process and aberrant healing and fibrotic damage associated with a diverse set of disease states.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The International Journal of Biochemistry & Cell Biology - Volume 42, Issue 4, April 2010, Pages 535–542
Journal: The International Journal of Biochemistry & Cell Biology - Volume 42, Issue 4, April 2010, Pages 535–542
نویسندگان
Ellen C. Keeley, Borna Mehrad, Robert M. Strieter,