کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1988423 1540394 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Structural studies on the chiral selector capacity of cyclodextrin derivatives
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Structural studies on the chiral selector capacity of cyclodextrin derivatives
چکیده انگلیسی
Chromatographic separation of enantiomers to assure or enhance chiral purity is of considerable importance and can be achieved by the use of selectors of great structural variety. Cyclodextrins are an important and frequently used class, and they are multimodal selectors since multiple chiral interactions are possible by very different mechanisms. Here, the results of a preliminary examination on the possible value of computational molecular modeling approaches for the predictability of cyclodextrin selector effects for compounds that possess both geometrical and optical isomerism are presented. Interactions between various cyclodextrins and pyrethroic acids are modeled, interpreted, and compared to experimental capillary electrophoresis data.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biochemical and Biophysical Methods - Volume 70, Issue 6, 24 April 2008, Pages 1276-1282
نویسندگان
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