کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1994358 1064771 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Protocols for cardiac differentiation of embryonic stem cells
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Protocols for cardiac differentiation of embryonic stem cells
چکیده انگلیسی

Both mouse and human embryonic stem (ES) cells provide a powerful model of early cardiogenesis. Furthermore engineering of cardiac progenitors or cardiomyocytes from ES cells offers a tool for drug screening in toxicology or to search for molecules to improve and scale up the process of cardiac differentiation using high throughput screening technology. Spontaneous differentiation of ES cells into cardiomyocytes is however limited. Herein, I described simple protocols to commit both mouse and human ES cells toward a cardiac lineage and in turn to improve the process of in vitro differentiation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Methods - Volume 45, Issue 2, June 2008, Pages 168–171
نویسندگان
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