کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1995365 | 1064965 | 2009 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Acute kidney injury and lung dysfunction: A paradigm for remote organ effects of kidney disease?
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
An increasing body of evidence suggests that the deleterious effects of Acute Kidney Injury (AKI) on remote organ function could, at least in part, be due to loss of the normal balance of immune, inflammatory, and soluble mediator metabolism that attends injury of the tubular epithelium. Such dysregulation, acting at least in part on endothelium, leads to compromise of remote organ function. Kidney–lung interaction in the setting of AKI therefore constitutes not only a pressing clinical problem, but also an illuminating framework in which to consider possible mechanisms by which renal diseases exert such deleterious effects on patient outcomes, even when dialysis is provided.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Microvascular Research - Volume 77, Issue 1, January 2009, Pages 8–12
Journal: Microvascular Research - Volume 77, Issue 1, January 2009, Pages 8–12
نویسندگان
J.D. Paladino, J.R. Hotchkiss, H. Rabb,