کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2090828 1081520 2009 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Recent advances in peptide probe-based biosensors for detection of infectious agents
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
پیش نمایش صفحه اول مقاله
Recent advances in peptide probe-based biosensors for detection of infectious agents
چکیده انگلیسی

Recent biological terrorism threats and outbreaks of microbial pathogens clearly emphasize the need for biosensors that can quickly and accurately identify infectious agents. The majority of rapid biosensors generate detectable signals when a molecular probe in the detector interacts with an analyte of interest. Analytes may be whole bacterial or fungal cells, virus particles, or specific molecules, such as chemicals or protein toxins, produced by the infectious agent. Peptides and nucleic acids are most commonly used as probes in biosensors because of their versatility in forming various tertiary structures. The interaction between the probe and the analyte can be detected by various sensor platforms, including quartz crystal microbalances, surface acoustical waves, surface plasmon resonance, amperometrics, and magnetoelastics. The field of biosensors is constantly evolving to develop devices that have higher sensitivity and specificity, and are smaller, portable, and cost-effective. This mini review discusses recent advances in peptide-dependent rapid biosensors and their applications as well as relative advantages and disadvantages of each technology.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Microbiological Methods - Volume 78, Issue 1, July 2009, Pages 10–19
نویسندگان
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