کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2404160 1102956 2010 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Is it cost-effective to introduce rotavirus vaccination in the Dutch national immunization program?
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Is it cost-effective to introduce rotavirus vaccination in the Dutch national immunization program?
چکیده انگلیسی

This study assessed whether the inclusion of two rotavirus (RV) vaccines in the Dutch national immunization programme is cost-effective. Costs and outcomes in unvaccinated and vaccinated populations are compared for a time period of 20 years. In the baseline, assuming competitive market forces in relation to vaccine costs, Rotarix® is more cost-effective than RotaTeq®, resulting in a cost-utility ratio (CUR) of € 53,000 per DALY (third payer perspective) and € 49,000 per DALY (societal perspective), but both considered as being not cost-effective. Vaccine-related costs, annual epidemic-size, and indirect protection are the major factors that determine cost-effectiveness of RV vaccination.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 28, Issue 14, 19 March 2010, Pages 2624–2635
نویسندگان
, , , , , ,