کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2404469 | 1102979 | 2012 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: The concept of vaccination failure The concept of vaccination failure](/preview/png/2404469.png)
Despite remarkable success of immunization programmes on a global perspective, vaccines are neither 100% efficacious nor 100% effective. Therefore, vaccination failure, i.e. occurrence of a specific disease in an individual despite previous vaccination, may occur. Vaccination failure may be due to actual vaccine failure or failure to vaccinate appropriately.Universally accepted concepts and definitions of vaccination failure are required to assess and compare the benefit of vaccines used in populations. Here we propose general definitions for types of vaccination failure. In the future, these should be complemented by specific definitions for specific vaccines as needed depending on public health considerations.
► Vaccines for humans have been proven to be highly successful.
► Occurrence of a specific disease in an individual despite previous vaccination may be considered a vaccine failure.
► We propose general definitions for different types of vaccination failure.
► In the future, these should be complemented by specific definitions for specific vaccines.
Journal: Vaccine - Volume 30, Issue 7, 8 February 2012, Pages 1265–1268