کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2404745 1102995 2010 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Echinacea purpurea aerial extract alters course of influenza infection in mice
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Echinacea purpurea aerial extract alters course of influenza infection in mice
چکیده انگلیسی

Influenza infection is a major clinical problem and Echinacea purpurea, a widely consumed botanical product, is purported to alter the course of respiratory infections including influenza. Mice infected with WSN influenza A and treated with E. purpurea polysaccharide extract had less weight loss than untreated mice but similar pulmonary viral titers. Echinacea-treated mice had lower systemic and pulmonary KC and IL-10 levels and lower systemic IFN-γ levels following influenza infection. These suggest that E. purpurea alters the clinical course of influenza infection in mice through modulation of cytokines and not direct antiviral activity.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 28, Issue 23, 21 May 2010, Pages 3956–3962
نویسندگان
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