کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2405085 | 1103012 | 2009 | 8 صفحه PDF | دانلود رایگان |
With a retrospective study of invasive pneumococcal disease (IPD) surveillance data representative for ∼25% of the Dutch population (1275 hospitalized cases) over the period June 2004–June 2006 prior to the implementation of the 7-valent pneumococcal conjugate vaccine (PCV7), the aim was to provide baseline data on IPD for the interpretation of changes after implementation of conjugate vaccines. The IPD incidence peaked in 3–5-mnth-olds (63 cases per 100,000 persons yearly) and increased in adulthood, particularly after the age of 60 yrs, from 26 cases in 60–64-yr-olds to 97 cases per 100,000 in persons ≥90 yrs. Beyond the age of 4 yrs, 19% of IPD patients were immunocompromised, and this considerable percentage may have implications for vaccine efficacy.
Journal: Vaccine - Volume 27, Issue 17, 14 April 2009, Pages 2394–2401