کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2405611 1103042 2010 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Overview of the development and current use of CRM197 conjugate vaccines for pediatric use
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Overview of the development and current use of CRM197 conjugate vaccines for pediatric use
چکیده انگلیسی

Glycoconjugate vaccines have been proven safe and effective against various diseases in children. Although these vaccines have a history of effectiveness, there are still many unanswered questions to be addressed, including conjugate interference when multiple vaccines are administered at one time, expansion of serotype coverage, effectiveness in special populations, and issues relating to conjugate vaccine use in the developing world. This paper focuses on the use of CRM197 as a carrier protein, contrasting it to other carrier proteins used in single-antigen pediatric vaccines as well as identifying areas for future study.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 28, Issue 27, 17 June 2010, Pages 4335–4339
نویسندگان
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