کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2406809 1103097 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Population-based surveillance for severe rotavirus gastroenteritis in children in Karachi, Pakistan
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Population-based surveillance for severe rotavirus gastroenteritis in children in Karachi, Pakistan
چکیده انگلیسی

The incidence of rotavirus-associated severe diarrhoea and distribution of rotavirus genotypes in children less than five years of age was determined in two low-income communities in Karachi, Pakistan. Over a two-year period, 717 children met eligibility criteria for severe diarrhoea and stools were obtained from 575 (80%) with 97 (17%) being rotavirus positive. Adjusted annual rates of severe rotavirus diarrhoea in children less than five years and less than one year were respectively 5.7 and 16.9 per 1000 in community A, and 8.1 and 25.4 per 1000 child years of observation in community B. An estimated 1 in 40 infants experience a severe episode of rotavirus gastroenteritis annually in Pakistan. The most common rotavirus strains were G9P[8] (15%), G1P[8] (13%) and G1[P4] (8.4%). This information will inform policy decisions about the introduction of rotavirus vaccines.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 27, Supplement 5, 20 November 2009, Pages F25–F30
نویسندگان
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