کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2407085 1103111 2007 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Changing epidemiology of invasive pneumococcal disease in central Australia prior to conjugate vaccine: A 16-year study
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Changing epidemiology of invasive pneumococcal disease in central Australia prior to conjugate vaccine: A 16-year study
چکیده انگلیسی

This study reports a 16-year prospective surveillance of invasive disease isolates in central Australian Aborigines. There were 621 (89.6% of total) isolates recovered from Aborigines. The mortality in children less than 5 years of age was 4% but rose to 34.5% in those over 49 years of age. The study documented continuing high rates of disease overall, but with significant reductions in incidence rates for children. In children under 2 years of age, the incidence fell by 32% from 2053 per 100,000 in the period 1985–1990 to 1184 per 100,000 in the period 1996–2000. Rates of disease in adults showed no reduction despite an adult immunisation programme with 23 valent vaccine which occurred in the 1990s. Epidemics of serotypes 1, 5 and 12F were documented during the study period.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 25, Issue 13, 22 March 2007, Pages 2375–2378
نویسندگان
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