کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2407190 | 1103114 | 2009 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Possible autoimmune reactions following smallpox vaccination: The biologic false positive test for syphilis
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Due to the threat of bioterrorism, large-scale clinical trials of a new cell culture smallpox vaccine were conducted. Biologically false positive (BFR) serological reactions to viruses (hepatitis B and C, HIV) and syphilis were evaluated. BPR rapid reagin tests (RPR) to syphilis occurred in 19% and false positive tests for antibody to hepatitis B in 3.3% of 90 healthy adults undergoing primary vaccination. Most subjects (94%) were RPR-positive on Day 15 after vaccination and all seroreverted within 2 months thereafter. One subject with myocarditis was RPR-negative. One RPR-positive and 1 RPR-negative subject had elevated CK-MB enzymes without other evidence for myocarditis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 27, Issue 10, 4 March 2009, Pages 1645–1650
Journal: Vaccine - Volume 27, Issue 10, 4 March 2009, Pages 1645–1650
نویسندگان
Thomas P. Monath, Sharon E. Frey,