کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2408520 1103177 2007 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Impact of a targeted hepatitis B vaccination program in Amsterdam, The Netherlands
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Impact of a targeted hepatitis B vaccination program in Amsterdam, The Netherlands
چکیده انگلیسی

To evaluate hepatitis B virus (HBV) risk group vaccination in Amsterdam, which started in 1998, we examined 342 reported acute HBV-cases and sequenced 85 DNA isolates. The reported number of cases declined from 214 in 1992–1997 to 128 in 1998–2003, due to a decline in injecting drug users (IDU) and their heterosexual partners. Phylogenetic analyses showed that after 1998, the IDU cluster nearly disappeared, probably due to a decline in injecting. Acute HBV remained stable among men having sex with men; given their increased sexual risk behavior, vaccination has probably prevented an increase in their acute infections. Currently, 48–72% of the people who should be included in the program are still susceptible to HBV.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 25, Issue 14, 30 March 2007, Pages 2698–2705
نویسندگان
, , , , , , ,