کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2408520 | 1103177 | 2007 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Impact of a targeted hepatitis B vaccination program in Amsterdam, The Netherlands
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
To evaluate hepatitis B virus (HBV) risk group vaccination in Amsterdam, which started in 1998, we examined 342 reported acute HBV-cases and sequenced 85 DNA isolates. The reported number of cases declined from 214 in 1992–1997 to 128 in 1998–2003, due to a decline in injecting drug users (IDU) and their heterosexual partners. Phylogenetic analyses showed that after 1998, the IDU cluster nearly disappeared, probably due to a decline in injecting. Acute HBV remained stable among men having sex with men; given their increased sexual risk behavior, vaccination has probably prevented an increase in their acute infections. Currently, 48–72% of the people who should be included in the program are still susceptible to HBV.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 25, Issue 14, 30 March 2007, Pages 2698–2705
Journal: Vaccine - Volume 25, Issue 14, 30 March 2007, Pages 2698–2705
نویسندگان
Robin van Houdt, Gerard J.B. Sonder, Nicole H.T.M. Dukers, Lian P.M.J. Bovee, Anneke van den Hoek, Roel A. Coutinho, Sylvia M. Bruisten,