کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2409600 1103224 2007 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Comparative host–parasite relationships in ovine toxoplasmosis and bovine neosporosis and strategies for vaccination
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Comparative host–parasite relationships in ovine toxoplasmosis and bovine neosporosis and strategies for vaccination
چکیده انگلیسی

Toxoplasma gondii and Neospora caninum are important causes of reproductive loss in ruminant species worldwide. Both parasites cause disease during pregnancy that may result in foetal death or birth of live congenitally infected offspring. T. gondii is also an important human pathogen with the main risk groups including pregnant women and immuno-compromised individuals, although clinical disease has also been observed in outbreaks among immuno-competent people. While the two parasites are closely related there are distinct differences between the two in their interactions with different host species and subsequent clinical outcome. This paper discusses the respective host–parasite relationships in ovine toxoplasmosis and bovine neosporosis and how the immune response may be host-protective, parasite-protective or contribute to disease pathogenesis, and how this knowledge may help in the development of more effective and targeted vaccination strategies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 25, Issue 30, 26 July 2007, Pages 5495–5503
نویسندگان
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