کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2436791 1107354 2009 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Sexual recombination punctuated by outbreaks and clonal expansions predicts Toxoplasma gondii population genetics
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی انگل شناسی
پیش نمایش صفحه اول مقاله
Sexual recombination punctuated by outbreaks and clonal expansions predicts Toxoplasma gondii population genetics
چکیده انگلیسی

The cosmopolitan parasitic pathogen Toxoplasma gondii is capable of infecting essentially any warm-blooded vertebrate worldwide, including most birds and mammals, and establishes chronic infections in one-third of the globe’s human population. The success of this highly prevalent zoonosis is largely the result of its ability to propagate both sexually and clonally. Frequent genetic exchanges via sexual recombination among extant parasite lineages that mix in the definitive felid host produces new lines that emerge to expand the parasite’s host range and cause outbreaks. Highly successful lines spread clonally via carnivorism and in some cases sweep to pandemic levels. The extent to which sexual reproduction versus clonal expansion shapes Toxoplasma’s current, global population genetic structure is the central question this review will attempt to answer.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal for Parasitology - Volume 39, Issue 8, 1 July 2009, Pages 925–933
نویسندگان
, ,