کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2466440 1555336 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Controlling equine influenza: Traditional to next generation serological assays
ترجمه فارسی عنوان
کنترل آنفولانزای مرغی: سنتی برای آزمایشات سرولوژیک نسل بعدی
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
چکیده انگلیسی


• Equine serological assays – choosing the right assay for the right application.
• ELISA and HI assays are beneficial for diagnostic purposes.
• SRH and VN more suited for vaccine efficacy testing.
• The PVNA is a promising assay for the future of serology.

Serological assays provide an indirect route for the recognition of infectious agents via the detection of antibodies against the infectious agent of interest within serum. Serological assays for equine influenza A virus can be applied for different purposes: diagnosing infections; subtyping isolates; surveillance of circulating strains; and to evaluate the efficacy of vaccines before they reach the market. Haemagglutination inhibition (HI) and single radial haemolysis (SRH) assays are most commonly used in the equine field. This review outlines how both these assays together with virus neutralization (VN) and ELISA are performed, interpreted and applied for the control of equine influenza, giving the limitations and advantages of each. The pseudotyped virus neutralization assay (PVNA) is also discussed as a promising prospect for the future of equine influenza virus serology.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Veterinary Microbiology - Volume 187, 1 May 2016, Pages 15–20
نویسندگان
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