کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2467361 1555399 2011 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mycobacterium bovis antigens for the differential diagnosis of vaccinated and infected cattle
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
Mycobacterium bovis antigens for the differential diagnosis of vaccinated and infected cattle
چکیده انگلیسی

The urgency for new and improved cattle vaccines and diagnostic reagents for Bovine tuberculosis (TB) has made their development a research priority in Great Britain (GB). Significant progress has been made to develop specific antigens that allow the differentiation of BCG vaccinated and Mycobacterium bovis infected cattle (DIVA test). This has been greatly facilitated by the completion of the genome sequences of M. tuberculosis, M. bovis and BCG Pasteur and the subsequent application of comparative genome and transcriptome analysis to define DIVA antigens that complemented the prototype DIVA antigens ESAT-6 and CFP-10 by increasing their test sensitivity. Finally, we present an up-date of our current approaches in this area.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Veterinary Microbiology - Volume 151, Issues 1–2, 5 July 2011, Pages 8–13
نویسندگان
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